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1

Retinal Pigment Epithelium in Health and Disease ||

Klettner, Alexa Karina, Dithmar, Stefan

Year:

2020

Language:

english

File:

PDF, 20.92 MB

english, 2020

2

Interaction of inflammatorily activated retinal pigment epithelium with retinal microglia and neuronal cells

Dietrich, Luisa, Lucius, Ralph, Roider, Johann, Klettner, Alexa

Journal:

Experimental Eye Research

Year:

2020

File:

PDF, 37.32 MB

2020

3

Differences in uptake and intracellular fate between Bevacizumab and Aflibercept after repetitive long-term treatment in the RPE

Borchers, Laura, Roider, Johann, Klettner, Alexa

Journal:

Ophthalmic Research

Year:

2020

File:

PDF, 24.82 MB

2020

4

Different properties of VEGF-antagonists: Bevacizumab but not Ranibizumab accumulates in RPE cells

Alexa Karina Klettner, Marie-Luise Kruse, Tim Meyer, Daniela Wesch, Dieter Kabelitz, Johann Roider

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2009

Language:

english

File:

PDF, 482 KB

english, 2009

5

Constitutive and oxidative-stress-induced expression of VEGF in the RPE are differently regulated by different Mitogen-activated protein kinases

Alexa Klettner, Johann Roider

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2009

Language:

english

File:

PDF, 167 KB

english, 2009

6

Intracellular bevacizumab reduces phagocytotic uptake in RPE cells

Alexa Klettner, Friederike Möhle, Johann Roider

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2010

Language:

english

File:

PDF, 374 KB

english, 2010

7

Influence of alcohol consumption on incidence and severity of open-globe eye injuries in adults

Florian Rüfer, Andrea Peters, Alexa Klettner, Felix Treumer, Johann Roider

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2011

Language:

english

File:

PDF, 140 KB

english, 2011

8

Nicotine reduces VEGF-secretion and phagocytotic activity in porcine RPE

Alexa Karina Klettner, Johanna Doths, Johann Roider

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2012

Language:

english

File:

PDF, 211 KB

english, 2012

9

The immunophilin-ligands FK506 and V-10,367 mediate neuroprotection by the heat shock response

Alexa Klettner, Thomas Herdegen

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 279 KB

english, 2003

10

Influence of atmospheric pressure on postoperative decompensation of intraocular pressure in perfluorethane-filled eyes after vitrectomy

Florian Rüfer, Andrea Kohlmann, Christian Kandzia, Alexa Klettner, Johann Roider

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2012

Language:

english

File:

PDF, 115 KB

english, 2012

11

Multilayered Gore-Tex Patch for Temporary Coverage of Deep Noninfectious Corneal Defects: Surgical Procedure and Clinical Experience

Florian Rüfer, Johannes Eisenack, Alexa Klettner, Rainald Zeuner, Jost Hillenkamp, Gundolf Westphal, Johann Roider, Bernhard Nölle

Journal:

American Journal of Ophthalmology

Year:

2011

Language:

english

File:

PDF, 2.25 MB

english, 2011

12

Anterior chamber depth and iridocorneal angle in healthy White subjects: effects of age, gender and refraction

Florian Rüfer, Anke Schröder, Alexa Klettner, Adjoa Frimpong-Boateng, Johann B Roider, Carl Erb

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2010

Language:

english

File:

PDF, 282 KB

english, 2010

13

Age-corrected reference values for the Heidelberg multi-color anomaloscope

Florian Rüfer, Benno Sauter, Alexa Klettner, Katja Göbel, Josef Flammer, Carl Erb

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2012

Language:

english

File:

PDF, 341 KB

english, 2012

14

Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization

Klettner, Alexa, Kauppinen, Anu, Blasiak, Janusz, Roider, Johan, Salminen, Antero, Kaarniranta, Kai

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 727 KB

english, 2013

15

Isolation of porcine monocyte population: a simple and efficient method

Berg, Christin, Wilker, Sebastian, Roider, Johann, Klettner, Alexa

Journal:

Veterinary Research Communications

Year:

2013

Language:

english

File:

PDF, 163 KB

english, 2013

16

Retinal pigment epithelium cells alter the pro-inflammatory response of retinal microglia to TLR-3 stimulation

Klettner, Alexa, Hamann, Timothy, Schlüter, Karen, Lucius, Ralph, Roider, Johann

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2014

Language:

english

File:

PDF, 621 KB

english, 2014

17

Oxidative Stress Induces Biphasic ERK1/2 Activation in the RPE with Distinct Effects on Cell Survival at Early and Late Activation

Koinzer, Stefan, Reinecke, Kirstin, Herdegen, Thomas, Roider, Johann, Klettner, Alexa

Journal:

Current Eye Research

Year:

2015

Language:

english

File:

PDF, 208 KB

english, 2015

18

Comparison of the influence of aerobic and resistance exercise of the upper and lower limb on intraocular pressure

Rüfer, Florian, Schiller, Johanna, Klettner, Alexa, Lanzl, Ines, Roider, Johann, Weisser, Burkhard

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2014

Language:

english

File:

PDF, 130 KB

english, 2014

19

Intracellular pathways following uptake of bevacizumab in RPE cells

Aboul Naga, Shereen Hassan, Dithmer, Michaela, Chitadze, Guranda, Kabelitz, Dieter, Lucius, Ralph, Roider, Johann, Klettner, Alexa

Journal:

Experimental Eye Research

Year:

2015

Language:

english

File:

PDF, 6.80 MB

english, 2015

20

Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro , and its toxicity is mediated by p38

Klettner, Alexa, Koinzer, Stefan, Waetzig, Vicki, Herdegen, Thomas, Roider, Johann

Journal:

Cutaneous and Ocular Toxicology

Year:

2010

Language:

english

File:

PDF, 873 KB

english, 2010

21

Comparison of the efficacy of aflibercept, ranibizumab, and bevacizumab in an RPE/choroid organ culture

Klettner, Alexa, Recber, Muhammed, Roider, Johann

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2014

Language:

english

File:

PDF, 398 KB

english, 2014

22

Compatibility of recombinant tissue plasminogen activator (rtPA) and aflibercept or ranibizumab coapplied for neovascular age-related macular degeneration with submacular haemorrhage

Klettner, Alexa, Grotelüschen, Simon, Treumer, Felix, Roider, Johann, Hillenkamp, Jost

Journal:

British Journal of Ophthalmology

Year:

2015

Language:

english

File:

PDF, 1.72 MB

english, 2015

23

Comparison of Bevacizumab, Ranibizumab, and Pegaptanib In Vitro: Efficiency and Possible Additional Pathways

Klettner, Alexa, Roider, Johann

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

24

The retinal pigment epithelium (RPE) induces FasL and reduces iNOS and Cox2 in primary monocytes

Hettich, Christin, Wilker, Sebastian, Mentlein, Rolf, Lucius, Ralph, Roider, Johann, Klettner, Alexa

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2014

Language:

english

File:

PDF, 465 KB

english, 2014

25

Hyperthermia-induced upregulation of vascular endothelial growth factor in retinal pigment epithelial cells is regulated by mitogen-activated protein kinases

Faby, Hendrik, Hillenkamp, Jost, Roider, Johann, Klettner, Alexa

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

26

Change of Morphological and Functional Characteristics of Retinal Pigment Epithelium Cells during Cultivation of Retinal Pigment Epithelium-Choroid Perfusion Tissue Culture

Miura, Yoko, Klettner, Alexa, Noelle, Bernhard, Hasselbach, Heike, Roider, Johann

Journal:

Ophthalmic Research

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

27

Toll-like receptor 3 activation in retinal pigment epithelium cells - Mitogen-activated protein kinase pathways of cell death and vascular endothelial growth factor secretion

Klettner, Alexa, Koinzer, Stefan, Meyer, Tim, Roider, Johann

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2013

Language:

english

File:

PDF, 490 KB

english, 2013

28

Quantifying FITC-Labeled Latex Beads Opsonized with Photoreceptor Outer Segment Fragments: An Easy and Inexpensive Method of Investigating Phagocytosis in Retinal Pigment Epithelium Cells

Klettner, Alexa, Möhle, Friederike, Lucius, Ralph, Roider, Johann

Journal:

Ophthalmic Research

Year:

2011

Language:

english

File:

PDF, 296 KB

english, 2011

29

CORRELATION OF FUNDUS AUTOFLUORESCENCE, SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY, AND MICROPERIMETRY IN LATE DEFEROXAMINE MACULOPATHY

Koinzer, Stefan, Klettner, Alexa, Treumer, Felix, Nölle, Bernhard, Roider, Johann

Journal:

Retinal Cases & Brief Reports

Year:

2012

Language:

english

File:

PDF, 860 KB

english, 2012

30

Open globe injuries by rotating wire brushes

Purtskhvanidze, Konstantine, Klettner, Alexa, Roider, Johann, Rüfer, Florian

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2013

Language:

english

File:

PDF, 215 KB

english, 2013

31

Compatibility of Recombinant Tissue Plasminogen Activator and Bevacizumab Co-Applied for Neovascular Age-Related Macular Degeneration With Submacular Hemorrhage

Klettner, Alexa, Puls, Svenja, Treumer, Felix, Roider, Johann, Hillenkamp, Jost

Journal:

Archives of Ophthalmology

Year:

2012

Language:

english

File:

PDF, 451 KB

english, 2012

32

The role of Fc-receptors in the uptake and transport of therapeutic antibodies in the retinal pigment epithelium

Dithmer, Michaela, Hattermann, Kirsten, Pomarius, Prasti, Aboul Naga, Shereen Hassan, Meyer, Tim, Mentlein, Rolf, Roider, Johann, Klettner, Alexa

Journal:

Experimental Eye Research

Year:

2016

Language:

english

File:

PDF, 12.77 MB

english, 2016

33

SAFETY TESTING OF INDOCYANINE GREEN WITH DIFFERENT SURGICAL LIGHT SOURCES AND THE PROTECTIVE EFFECT OF OPTICAL FILTERS

HILLENKAMP, JOST, DYDYKINA, SOFIA, KLETTNER, ALEXA, TREUMER, FELIX, VASOLD, RUDOLF, BÄUMLER, WOLFGANG, ROIDER, JOHANN

Journal:

Year:

2010

Language:

english

File:

PDF, 336 KB

english, 2010

34

Alpha synuclein and crystallin expression in human lens in Parkinson's disease

Klettner, Alexa, Richert, Elisabeth, Kuhlenbäumer, Gregor, Nölle, Bernhard, Bhatia, Kailash P., Deuschl, Günter, Roider, Johann, Schneider, Susanne A.

Journal:

Movement Disorders

Year:

2016

Language:

english

File:

PDF, 809 KB

english, 2016

35

Characterization of the Thinnest Point of the Cornea Compared With the Central Corneal Thickness in Normal Subjects

Rüfer, Florian, Sander, Sebastian, Klettner, Alexa, Frimpong-Boateng, Adjoa, Erb, Carl

Journal:

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

36

Reduction of GAPDH in lenses of Parkinson's disease patients: A possible new biomarker

Klettner, Alexa, Tholey, Andreas, Wiegandt, Alena, Richert, Elisabeth, Nölle, Bernhard, Deuschl, Günther, Roider, Johann, Schneider, Susanne A.

Journal:

Movement Disorders

Year:

2016

Language:

english

File:

PDF, 306 KB

english, 2016

37

Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice

Tode, Jan, Richert, Elisabeth, Koinzer, Stefan, Klettner, Alexa, Pickhinke, Ute, Garbers, Christoph, Rose-John, Stefan, Nölle, Bernhard, Roider, Johann

Journal:

Year:

2017

Language:

english

File:

PDF, 935 KB

english, 2017

38

Ocular Trauma Score as prognostic value in traumatic ocular injuries due to rotating wire brushes

Purtskhvanidze, Konstantine, Rüfer, Florian, Klettner, Alexa, Borzikowsky, Christoph, Roider, Johann

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2017

Language:

english

File:

PDF, 431 KB

english, 2017

39

Long-term treatment with anti-VEGF does not induce cell aging in primary retinal pigment epithelium

Schottler, Johann, Randoll, Niklas, Lucius, Ralph, Caliebe, Amke, Roider, Johann, Klettner, Alexa

Journal:

Experimental Eye Research

Year:

2018

Language:

english

File:

PDF, 1.55 MB

english, 2018

40

Fucoidan Reduces Secretion and Expression of Vascular Endothelial Growth Factor in the Retinal Pigment Epithelium and Reduces Angiogenesis In Vitro

Dithmer, Michaela, Fuchs, Sabine, Shi, Yang, Schmidt, Harald, Richert, Elisabeth, Roider, Johann, Klettner, Alexa, Acott, Ted S.

Journal:

Year:

2014

Language:

english

File:

PDF, 923 KB

english, 2014

41

Oxidative stress induced cellular signaling in RPE cells

Klettner, Alexa

Journal:

Frontiers in Bioscience

Year:

2012

Language:

english

File:

PDF, 635 KB

english, 2012

42

Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines

Dithmer, Michaela, Kirsch, Anna-Maria, Richert, Elisabeth, Fuchs, Sabine, Wang, Fanlu, Schmidt, Harald, Coupland, Sarah, Roider, Johann, Klettner, Alexa

Journal:

Year:

2017

Language:

english

File:

PDF, 3.55 MB

english, 2017

43

Fucoidan as a Potential Therapeutic for Major Blinding Diseases—A Hypothesis

Klettner, Alexa

Journal:

Year:

2016

File:

PDF, 596 KB

2016

44

Fucoidan as a Potential Therapeutic for Major Blinding Diseases—A Hypothesis

Klettner, Alexa

Journal:

Year:

2016

Language:

english

File:

PDF, 596 KB

english, 2016

45

Release of Different Cell Mediators During Retinal Pigment Epithelium Regeneration Following Selective Retina Therapy

Richert, Elisabeth, Koinzer, Stefan, Tode, Jan, Schlott, Kerstin, Brinkmann, Ralf, Hillenkamp, Jost, Klettner, Alexa, Roider, Johann

Journal:

Investigative Opthalmology & Visual Science

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

46

The Antiproliferative Effect of Bevacizumab on Human Tenon Fibroblasts Is Not Mediated by Vascular Endothelial Growth Factor Inhibition

Fischer, Charlotte V., Mans, Viktoria, Horn, Maren, Naxer, Sabine, Klettner, Alexa, van Oterendorp, Christian

Journal:

Investigative Opthalmology & Visual Science

Year:

2016

Language:

english

File:

PDF, 2.63 MB

english, 2016

47

Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models

Tode, Jan, Richert, Elisabeth, Koinzer, Stefan, Klettner, Alexa, Burchard, Claus von der, Brinkmann, Ralf, Lucius, Ralph, Roider, Johann

Journal:

Translational Vision Science & Technology

Year:

2018

Language:

english

File:

PDF, 4.68 MB

english, 2018

48

Effects of Cytokine Activation and Oxidative Stress on the Function of the Human Embryonic Stem Cell–Derived Retinal Pigment Epithelial Cells

Juuti-Uusitalo, Kati, Nieminen, Monica, Treumer, Felix, Ampuja, Minna, Kallioniemi, Anne, Klettner, Alexa, Skottman, Heli

Journal:

Investigative Opthalmology & Visual Science

Year:

2015

File:

PDF, 1.09 MB

2015

49

Effects of Cytokine Activation and Oxidative Stress on the Function of the Human Embryonic Stem Cell–Derived Retinal Pigment Epithelial Cells

Juuti-Uusitalo, Kati, Nieminen, Monica, Treumer, Felix, Ampuja, Minna, Kallioniemi, Anne, Klettner, Alexa, Skottman, Heli

Journal:

Investigative Opthalmology & Visual Science

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

50

Effects of Fucoidans from Five Different Brown Algae on Oxidative Stress and VEGF Interference in Ocular Cells

Dörschmann, Philipp, Bittkau, Kaya Saskia, Neupane, Sandesh, Roider, Johann, Alban, Susanne, Klettner, Alexa

Journal:

Year:

2019

Language:

english

File:

PDF, 27.79 MB

english, 2019